ea0022p835 | Thyroid | ECE2010
Azevedo Teresa
, Martinho Mariana
, Martins Teresa
, Dias Florbela
, Cunha Nuno
, Valido Frederico
, Gervasio Helena
, Rodrigues Fernando
Introduction: Tyrosine Kinase Inhibitors (TKIs) are approved for the treatment of several cancers and can induce hypothyroidism by unclarified mechanisms.Objectives: To assess the prevalence of hypothyroidism in patients treated with TKIs.Methods: Retrospective review of clinical records of patients treated with TKIs in our institution between 2003 and 2009. We evaluated parameters such as sex, oncologic pathology, TKI used, TSH an...